CN
CN
  • Contact
  • Hangzhou Haoyang Biopharm Co. Ltd

  • 0571-26201624

  • dai-mingshu@hs-biopharm.com

  • 401E, Building 7, No. 22, Xinyan Road, Donghu Street, Yuhang District, Hangzhou, Zhejiang, China

    No.488-1, Donghu North Road, Donghu Street, Yuhang District, Hangzhou, Zhejiang, China

    2nd Floor, Building 41, Songgang Science and Technology City, Lingang District, Shanghai

  • 关注了解更多
Molecular Structure Design and Production
Evaluation of candidate drug molecules
Humanization Presentation
ADC Development

Evaluation of candidate drug molecules

Developability Assessments

Developability During Early Candidates Selection Period
Protein production in mammalian expression system (HEK293 or CHO)

  • In-silico analysis (critical PTM sites, pI, free cys, N-glycosylation )
  • Purification yield by ProA
  • Aggregation --- SEC-MALS
  • Hydrophilicity --- HIC-HPLC
  • Tm by DSF (Thermofluor)

image.png

Case Study

Initial-DAS

PTM Stress test